Biofreeze Cold Therapy Pain Relief Roll-on Biofreeze topical pain killing roll-on provides long-lasting relief from a range of ailments, including sporting injuries, back pain, strained muscles, painful joints and arthritis. Biofreeze works using cryotherapy, a process which dramatically cools the affected area to relieve pain in two ways, it reduces the blood supply to the painful area and reduces the ability of the nerves to conduct pain stimuli. The unique Biofreeze formula contains Ilex, a herb extracted from the holly shrub. Ingredients Isopropyl alcohol, Water, Herbal Extract (Ilex Paraguariensis), Carbomer, Triethanolamine, Menthol, Camphor, Silicon Dioxide, Methylparaben, Gylcerine, Propylene Glycol, FD C yellow #5 and FD C blue #1. Directions Adults and children 2 years of age and older: Apply to the affected area not more than 3 to 4 times daily. Children under 2 years of age: consult physician. Consult your physician before use if you are pregnant or nursing or have sensitive skin. Rub a thin film over desired area of the body, massage not necessary. Rinse with cool water