To all of our great customers: You may have noticed that some of our prices are much higher than normal. This is because Life Extension is enforcing a MAP - Minimum Advertised Price. This is the price we have to advertise, but we can sell for less. We can and will still sell to you at the low prices you have come to expect! Just use the "make offer" button and enter the price that you normally pay! If you don't know the price, just message and we will let you know. Thank you - we appreciate your business! **** NEW FROM LIFE EXTENSION! **** TWO BOTTLES FRESH PRODUCT! SHIPS TO YOU STRAIGHT FROM LIFE EXTENSION! BUY IT NOW AND SAVE! GEROPROTECT Autophagy Renew 30 vegetarian capsules Encourages ?cellular housekeeping? and longevity Live your longest, healthiest life with GEROPROTECT Autophagy Renew, a novel formula that encourages autophagy, the natural process for recycling cellular debris that can get in the way of healthy cell function. Overview As we age, our bodies get less adept at autophagy, the process for recycling debris in our cells that get in the way of normal function. Give that cellular recycling process a helping hand?so you can live your longest, healthiest life. GEROPROTECT Autophagy Renew contains a plant flavonoid, luteolin, and an alkaloid from pepper called piperlongumine, which support your body?s natural clean-up process. Give your body?s natural cellular recycling process a boost?so you can live your longest, healthiest life. GEROPROTECT Autophagy Renew Benefits Innovative longevity formula Helps your body function optimally, without cellular debris getting in the way Promotes healthy AMPK activity Encourages cells to recycle waste material Helps maintain cellular energy balance Recycling what?s inside: autophagy explained We know that recycling is good for the environment. But as it turns out, it?s also good for our cells: autophagy is a natural process by which cells clean up intra-cellular debris and other metabolic waste. Tiny cellular organelles called lysosomes breakdown and repurpose this spent material. So why does cellular autophagy matter? Because it helps our bodies conserve energy and function properly, which is essential to living a long, healthy life. Product Details Without autophagy, the insides of our cells would become cluttered and eventually cease to function. The problem is autophagy naturally decreases over time. But the right nutrients can encourage youthful, healthy autophagy at the cellular level?the hard part is figuring out which nutrients do the best job. Insilico Artificial Intelligence GEROPROTECT Autophagy Renew was created through a partnership with Insilico Medicine, Inc., who used their database of studies on geroprotectors to identify luteolin from Japanese sophora flower for its ability to promote autophagy?effects that are also supported by several pre-clinical studies. We added piperlongumine (a pepper alkaloid) because of our own extensive scientific review. Together, these nutrients have the potential to encourage healthy cellular autophagy?and with it, longevity. Luteolin Luteolin is a flavonoid present in fruits, vegetables and nutritious herbs. We get trace amounts of luteolin in our diets, but not nearly enough to encourage healthy cellular renewal. GEROPROTECT Autophagy Renew contains 165 mg of luteolin per serving. In pre-clinical studies, luteolin promoted autophagy, leading to a variety of health benefits, particularly in the brain. Luteolin supports the cellular pathways that encourage autophagy, such as AMPK signaling. Luteolin also promotes the generation of new lysosomes, the ?recycling plants? inside your cells that break down waste. Plus, luteolin inhibits the processes that discourage autophagy, such as mTOR signaling?a central regulator of cellular metabolism and proliferation. Piperlongumine Piperlongumine is a biologically active alkaloid found in pepper plants. In pre-clinical studies, piperlongumine was shown to activate autophagy as indicated by increased cellular markers called LC3-autophagosomes, structures involved in initiation of autophagy within a cell. Piperlongumine activates Beclin-1, a gene that triggers formation of these autophagosome structures. Beclin-1 dependent autophagy helps protect delicate mitochondria and helped inhibit inflammation to support cardiovascular health in an animal study. Our formula contains 10 mg of piperlongumine. Take alone or with Senolytic Activator While cellular housekeeping orchestrated by autophagy is a different process than the ones that govern the removal of senescent cells, they are complementary. Therefore, GEROPROTECT Autophagy Renew can be taken alone, or in conjunction with our Senolytic Activator formula. Supplement Facts Serving Size 1 vegetarian capsule Amount Per Serving Luteolin [from Japanese sophora (flower buds)] 165 mg Piperlongumine [from long pepper (root)] 10 mg Other ingredients: maltodextrin, vegetable cellulose (capsule), vegetable stearate, silica. ?Developed in collaboration with Insilico Medicine, Inc Non-GMO Dosage and Use Take one (1) capsule daily, or as recommended by a healthcare practitioner. RETURN POLICY: If you are not 100% satisfied with your purchase, please contact us IMMEDIATELY and we will make it right! We can only accept UNOPENED bottles for return or exchange.