Title: The Principles and Practice of Medicine: Designed for the Use of Practitioners and Students of Medicine Author: William Osler, M.D. Publisher: D. Appleton Co. Publishing Date: 1897 Edition: Second Edition Binding: Brown cloth hardcover Pages: 1,143 including index Illustrated: Some charts Interior Condition: Generally solid binding, complete and intact, with some netting showing on inside back board. A few light notes in ink by former owner on inside back board and last couple of blank pages. No other interior writing detected. Exterior Condition: Good, with edge and corner wear including fraying of top and bottom spine fabric, scuffs, 2" tear in fold along front board, a few ink spots on side pages Dust Jacket: No Size: 8vo ISBN: N/A Comments: A medical textbook by Sir William Osler. It was first published in 1892 while Osler was Professor of Medicine at Johns Hopkins University. It established Osler as the world's leading authority in the teaching of modern medicine. The textbook was translated into French, German, Russian, Portuguese, Spanish and Chinese, and for over 40 years it was the most significant medical textbook.